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KMID : 0644120120250020108
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Journal of Oriental Gynecology
2012 Volume.25 No. 2 p.108 ~ p.119
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The Compositional Differences of Sipjeondaebo-tang(Siquandabu-tang) Decoctions Extracted by Different Extraction Method and Extraction Time
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Kim Jung-Hoon
Seo Chang-Seob
Jeon Woo-Young
Shin Hyeun-Kyoo
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Abstract
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Objectives: This study was performed to compare the differences between decoctions extracted by different extraction method and extraction time.
Methods: Decoctions were prepared with pressurized or non-pressurized extraction for 60, 120 and 180min. The yield of extract, total soluble solid content, hydrogen ion concentration(pH) and the content of reference compound in Sipjeondaebo-tang (Siquandabu-tang) were investigated.
Results: While yields and the total soluble solid of decoction were higher in pressurized method proportional to extraction time, pH values were lower in pressurized method and showed decreasing values with increasing extraction time. Albilflorin, ferulic acid, nodakenin, coumarin, cinnamaldehyde and glycyrrhizin were contained in decoctions by pressurized extraction method more than non-pressurized method whereas the content of coumarin was higher in decoctions by non-pressurized extraction method. In addition, coumarin was extracted increasingly with extraction time in decoctions by pressurized method, however, nine compounds except cinnamaldehyde showed the tendency of increasing proportional to extraction time.
Conclusions: The results show that extraction methods including pressurized or non-pressurized extraction, and extraction time could affect the physicochemical characteristic or composition of Sipjeondaebo-tang(Siquandabu-tang) decoction.
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KEYWORD
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Compositional differences, Sipjeondaebo-tang(Siquandabu-tang) decoction, Extraction method, Extraction time
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